Driver fails to communicate with the device on HPZ2 machine

We are observing an issue with a device on one specific machine (HP Z2). The device contains a Bluetooth functionality and connects over USB to the host machine. If the device is connected directly to the host machine then the driver fails to communicate with the device at some point of time and the operation fails. The debug analysis so far shows that at some point we are not getting the data packets from the device. There is a 10 seconds gap in the driver logs and eventually the operation fails.

However if the device is connected to the host machine via an external USB hub then everything works fine. We have not observed any other USB related issues with the machine. Any suggestions for debugging this issue.
OS : Win10 64-Bit

For USB problems, get a bus analyzer (a real one, not wireshark). If your USB firmware is based on the chip vendor’s library - these free libraries sometimes are not very trustworthy.
And how Bluetooth is related?
– pa

also which protocol versions? USB 2? USB 3? does the external hub affect this? and what is the transfer mode and expected data rate?

Protocol version is USB 3. I am not sure how external USB hub is affecting this

what is the transfer mode and expected data rate?